Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201386 | 0.92 | CTSB (0.43) | MMP1MMP3ANPEPLTA4HLAP3 | |
| SCHEMBL11199575 | 0.91 | LTA4H (0.45) | MMP1MMP3ANPEPLTA4HLAP3 | |
| SCHEMBL8966089 | 0.83 | ANPEP (0.49) | ANPEPLTA4HCA12CA2CA7 | |
| SCHEMBL8966102 | 0.83 | ANPEP (0.49) | ANPEPLTA4HCA12CA2CA7 | |
| SCHEMBL7268410 | 0.75 | LTA4H (0.44) | MMP1MMP3ANPEPLTA4HRNPEP | |
| SCHEMBL7360135 | 0.74 | MMP1 (0.73) | MMP1MMP3CA12CA2CA7 | |
| SCHEMBL5492848 | 0.74 | LTA4H (0.50) | ANPEPLTA4HCA12CA2CA7 | |
| SCHEMBL28221965 | 0.74 | ANPEP (0.47) | ANPEPLTA4HCA12CA2CA7 | |
| Phenylalanine Methyl Ester SCHEMBL6748761 | 0.72 | SLC7A5 (0.58) | ANPEPLTA4HCA12CA2CA7 | |
| Phenylalanine Methyl Ester SCHEMBL9355479 | 0.71 | LAP3 (0.58) | ANPEPLTA4HLAP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075895-A2 | Pharmaceutical amides, and preparation, formulations and use thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-04-06 | — | — | EP | disclosed |