Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | QPCT | Q16769 | 2/20 | 0.56 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615813 | 0.88 | CLK4 (0.55) | NOTUMHRH3CLK4ADORA2AADORA1 | |
| SCHEMBL11326673 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1QPCTQPCTLMGAM | |
| SCHEMBL2833531 | 0.78 | KDM4E (0.69) | KDM4EALDH1A1MEN1KMT2AQPCT | |
| SCHEMBL3608623 | 0.77 | CHRNB2 (0.54) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11337791 | 0.75 | ALDH1A1 (1.00) | KDM4EALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL11324204 | 0.75 | HSD17B1 (0.76) | KDM4EALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL603197 | 0.75 | KDM4E (0.65) | KDM4EALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL3829254 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL368725 | 0.75 | KDM4E (0.65) | KDM4EALDH1A1MEN1KMT2AMGAM | |
| SCHEMBL45441 | 0.73 | KDM4E (0.67) | KDM4EALDH1A1MEN1KMT2AMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698641-A1 | Cationic 1,3,4-thiadiazole dyes | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0005783-B1 | IMIDAZO (2.1-B)-(1.3.4)-THIADIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BAYER AG (DE) | 1981-12-30 | — | — | EP | disclosed |
| US-4265898-A | ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |
| EP-0005783-A1 | Imidazo (2.1-b)-(1.3.4)-thiadiazoles, process for their preparation and their use in medicaments | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |