Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.59 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374582 | 1.00 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL6374591 | 1.00 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL65892 | 0.79 | DPYD (0.62) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL8776005 | 0.79 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL12903446 | 0.79 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL190003 | 0.79 | DPYD (0.62) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL190377 | 0.79 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL190378 | 0.79 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL933037 | 0.79 | DPYD (0.59) | DPYDATAD2MAPTGAAALDH1A1 | |
| SCHEMBL15798473 | 0.79 | DPYD (0.62) | DPYDATAD2MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521163-A | TREATMENT OF HERPES VIRUS WITH 1'-DEOXY-5-ETHYL-4'-THIO-BETA URIDINE | UNIVERSITY OF BIRMINGHAM (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0421777-B1 | Further antiviral pyrimidine nucleosides | UNIV BIRMINGHAM (GB) | 1996-02-28 | — | — | EP | disclosed |
| EP-0658166-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | THE UNIVERSITY OF BIRMINGHAM (GB) | 1995-06-21 | — | — | EP | disclosed |
| US-5356882-A | Treating herpes virus | UNIVERSITY OF BIRMINGHAM (GB) | 1994-10-18 | — | — | US | disclosed |
| WO-1994005687-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1994-03-17 | — | — | WO | disclosed |
| EP-0514036-A2 | Preparation of thionucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |
| WO-1991004982-A1 | FURTHER ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1991-04-18 | — | — | WO | disclosed |
| EP-0421777-A1 | Further antiviral pyrimidine nucleosides | THE UNIVERSITY OF BIRMINGHAM (GB) | 1991-04-10 | — | — | EP | disclosed |
| WO-1991001326-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1991-02-07 | — | — | WO | disclosed |
| EP-0409575-A1 | Antiviral pyrimidine nucleosides | THE UNIVERSITY OF BIRMINGHAM (GB) | 1991-01-23 | — | — | EP | disclosed |