Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11711740 | 0.85 | OPRM1 (0.44) | ALDH1A1KMT2AMAPTLMNATSHR | |
| SCHEMBL14246859 | 0.80 | KMT2A (0.58) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL10654318 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTLMNATSHR | |
| SCHEMBL28223342 | 0.70 | TRPA1 (0.45) | LMNAOPRM1PTGS2NPY1RHTT | |
| SCHEMBL20012731 | 0.70 | OPRL1 (0.59) | ALDH1A1KMT2AMAPTLMNATSHR | |
| SCHEMBL1535881 | 0.69 | SLC6A9 (0.43) | KMT2ATSHRMEN1OPRM1NPY1R | |
| SCHEMBL7828092 | 0.68 | SLC18A3 (0.66) | ALDH1A1KMT2AMAPTLMNATSHR | |
| SCHEMBL7826892 | 0.68 | SLC18A3 (0.66) | ALDH1A1KMT2AMAPTLMNATSHR | |
| SCHEMBL7826888 | 0.68 | SLC18A3 (0.66) | ALDH1A1KMT2AMAPTLMNATSHR | |
| SCHEMBL11558827 | 0.68 | ALDH1A1 (0.67) | ALDH1A1KMT2AMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512584-A | 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |