SCHEMBL8966927

SCHEMBL8966927

Bc1cccc(Cl)c1N(CCCC)CCCC

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
DRD2 P14416 1/20 0.35
DRD3 P35462 1/20 0.35
CRHR1 P34998 4/20 0.35
HPGD P15428 2/20 0.35
EGFR P00533 2/20 0.34
ALDH1A1 P00352 1/20 0.34
ERBB2 P04626 1/20 0.34
ESR1 P03372 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8966248 0.89 CRHR1 (0.42) DRD2DRD3CRHR1ESR1KDM4E
SCHEMBL8966971 0.82 KDM4E (0.37) LMNADRD2DRD3ALDH1A1ESR1
SCHEMBL8967009 0.71 CYP1A2 (0.35) LMNAALDH1A1HTTMEN1KMT2A
SCHEMBL11134202 0.71 ESR1 (0.42) LMNACRHR1HPGDEGFRALDH1A1
SCHEMBL22390022 0.70 ELANE (0.45) LMNACRHR1EGFRALDH1A1ESR1
SCHEMBL28122448 0.69 CRHR1 (0.38) LMNACRHR1HPGDEGFRALDH1A1
SCHEMBL8967322 0.67 CYP1A2 (0.34) LMNAALDH1A1KCNH2
SCHEMBL14432390 0.67 ELANE (0.43) CRHR1EGFRESR1
SCHEMBL10009760 0.66 CRHR1 (0.46) DRD2DRD3CRHR1ALDH1A1SMN1; SMN2
SCHEMBL2959244 0.66 LMNA (0.35) LMNADRD2DRD3CRHR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0519496-B1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same TONEN CORP (JP) 1996-05-22 EP disclosed
EP-0404503-B1 Boron-containing, silicon nitride-based ceramic shaped body production process TONEN CORP (JP) 1996-03-06 EP disclosed
EP-0389084-B1 Process for producing a polyborosilazane TONEN CORP (JP) 1995-09-20 EP disclosed
US-5292830-A Silane, silazane, boron block crosslinked copolymers TONEN CORPORATION (JP) 1994-03-08 US disclosed
EP-0519496-A1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same Tonen Corporation (JP) 1992-12-23 EP disclosed
US-5128286-A BORON-CONTAINING, SILICON NITRIDE-BASED CERAMIC SHAPED BODY TONEN CORPORATION (JP) 1992-07-07 US disclosed
US-5030744-A Polyborosilazane and process for producing same TONEN CORPORATION (JP) 1991-07-09 US disclosed
EP-0404503-A1 Boron-containing, silicon nitride-based ceramic shaped body production process Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0389084-A2 Process for producing a polyborosilazane Tonen Corporation (JP) 1990-09-26 EP disclosed