Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967035 | 0.86 | CDC25B (0.56) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28112142 | 0.83 | HTT (0.51) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL27883374 | 0.79 | MAPT (0.57) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8966935 | 0.77 | CDC25B (0.56) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1818841 | 0.77 | IRAK4 (0.54) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL4103770 | 0.76 | CDC25B (0.68) | CDC25BALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9504621 | 0.76 | WDR5 (0.54) | CDC25BALDH1A1KDM4EHPGDCYP2C9 | |
| SCHEMBL27840740 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL19612390 | 0.75 | SLC6A4 (0.39) | ALDH1A1KDM4ECYP2C9CA12CA1 | |
| SCHEMBL8967454 | 0.75 | LMNA (0.46) | CDC25BALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279466-B1 | NOVEL NAPHTHALENE DERIVATIVES AND ANTIALLERGY AND ANTI-INFLAMMATORY PHARMACEUTICALS | WARNER-LAMBERT COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| US-4767776-A | N-1H-tetrazol-5-yl-2-naphthalene carboxamides and their use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0279466-A2 | Novel naphthalene derivatives and antiallergy and anti-inflammatory pharmaceuticals | WARNER-LAMBERT COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |