Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795332 | 0.90 | ADRA1A (0.44) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B | |
| SCHEMBL9987818 | 0.76 | ADRA1A (0.54) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B | |
| SCHEMBL9988082 | 0.75 | ADRA2A (0.43) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B | |
| SCHEMBL29155816 | 0.75 | GID4 (0.52) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B | |
| SCHEMBL3668028 | 0.74 | ADRA2A (0.54) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B | |
| SCHEMBL2399221 | 0.73 | ADRA2A (0.43) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B | |
| SCHEMBL78975 | 0.73 | ADRA2A (0.43) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B | |
| SCHEMBL29842306 | 0.73 | GID4 (0.62) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B | |
| SCHEMBL395087 | 0.73 | GID4 (0.62) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B | |
| SCHEMBL4204524 | 0.72 | ADRA1A (0.59) | ADRA2AADRA1ACYP2D6ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585116-B1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LTD (GB) | 1996-02-28 | — | — | EP | claimed |
| EP-0585116-A1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LIMITED (GB) | 1994-03-02 | — | — | EP | claimed |
| US-5389684-A | Treats disorder of central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| EP-0585116-A1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |