Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967121 | 1.00 | PTGDR2 (0.47) | PTGDR2P2RX3KMT2AMEN1MAPT | |
| SCHEMBL9074423 | 0.87 | GAA (0.43) | P2RX3KMT2AMAPTLMNAGRM4 | |
| SCHEMBL9074428 | 0.87 | GAA (0.43) | P2RX3KMT2AMAPTLMNAGRM4 | |
| SCHEMBL8965614 | 0.83 | PTGDR2 (0.42) | PTGDR2P2RX3KMT2AMEN1MAPT | |
| SCHEMBL8965818 | 0.82 | PTGDR2 (0.43) | PTGDR2P2RX3KMT2AMEN1MAPT | |
| SCHEMBL8966397 | 0.75 | PPARA (0.43) | PTGDR2P2RX3KMT2AMEN1MAPT | |
| SCHEMBL5544242 | 0.73 | PTGDR2 (0.76) | PTGDR2KMT2AMEN1MAPTLMNA | |
| SCHEMBL9075427 | 0.72 | ALDH1A1 (0.41) | P2RX3KMT2AMAPTGRM4POLB | |
| SCHEMBL9075422 | 0.72 | ALDH1A1 (0.41) | P2RX3KMT2AMAPTGRM4POLB | |
| SCHEMBL4484508 | 0.71 | NPC1 (0.44) | PTGDR2P2RX3KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509857-B1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| EP-0509857-A1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-21 | — | — | EP | disclosed |