Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075427 | 0.85 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9075422 | 0.85 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL8967115 | 0.83 | PTGDR2 (0.47) | PTGDR2KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL8967121 | 0.83 | PTGDR2 (0.47) | PTGDR2KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL8966397 | 0.75 | PPARA (0.43) | PTGDR2KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL9074423 | 0.70 | GAA (0.43) | KDM4EALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL9074428 | 0.70 | GAA (0.43) | KDM4EALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL8965709 | 0.69 | ALDH1A1 (0.38) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL8966100 | 0.69 | ALDH1A1 (0.38) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL8965937 | 0.69 | P2RX3 (0.37) | KDM4EALDH1A1HPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509857-B1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| EP-0509857-A1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-21 | — | — | EP | disclosed |