Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076256 | 0.84 | ALDH1A1 (0.41) | PPARAALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL9076258 | 0.84 | ALDH1A1 (0.41) | PPARAALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL8965614 | 0.75 | PTGDR2 (0.42) | PAMALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL8967115 | 0.75 | PTGDR2 (0.47) | PAMALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL8967121 | 0.75 | PTGDR2 (0.47) | PAMALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL9075986 | 0.71 | KDM4E (0.38) | PAMALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL27558052 | 0.69 | KDM4E (0.53) | PAMALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL9690951 | 0.69 | ALOX15 (0.44) | RAB9ASMN1; SMN2MAPTPOLBPTGDR2 | |
| SCHEMBL6312946 | 0.69 | AKR1B1 (0.64) | PPARAPAMALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL6313137 | 0.69 | AKR1B1 (0.64) | PPARAPAMALDH1A1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509857-B1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| EP-0509857-A1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-21 | — | — | EP | disclosed |