Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8966348 | 0.99 | HDAC1 (0.48) | HDAC1HDAC6KMT2AMEN1USP2 | |
| SCHEMBL8967239 | 0.86 | LPAR1 (0.46) | HDAC1HDAC6KMT2AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL8966681 | 0.85 | LPAR1 (0.46) | HDAC1HDAC6KMT2AMEN1TSHR | |
| SCHEMBL8616017 | 0.85 | HDAC1 (0.47) | HDAC1HDAC6KMT2AMEN1USP2 | |
| Hydrochloric Acid SCHEMBL8966680 | 0.84 | ALDH1A1 (0.47) | KMT2AMEN1USP2MAPTTSHR | |
| Hydrochloric Acid SCHEMBL8620508 | 0.84 | HDAC1 (0.47) | HDAC1HDAC6KMT2AMEN1USP2 | |
| SCHEMBL6127323 | 0.82 | HDAC1 (0.61) | HDAC1HDAC6KMT2AMEN1USP2 | |
| Hydrochloric Acid SCHEMBL8794670 | 0.81 | POLB (0.39) | KMT2AMEN1MAPTTSHRTDP1 | |
| SCHEMBL8967342 | 0.81 | HDAC1 (0.44) | HDAC1KMT2AMEN1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL8966843 | 0.80 | L3MBTL1 (0.46) | HDAC1KMT2AMEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561147-A | ANTIINFLAMMATORY AGENT, ANTIPYRETIC, ANALGESICS, ANTIALLERGENS, IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-01 | — | — | US | disclosed |
| US-5457106-A | Antiinflammatory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| US-5389658-A | Administering as antipyretic, antiinflammatory, analgesic, antiallergic, or immunosupressive agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0612729-A2 | Pyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5246948-A | Antiinflammatory, antipyretic, analgesic, antiallergic, immunosupressing or immunomodulating activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0522606-A2 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-13 | — | — | EP | disclosed |