Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687324 | 0.79 | HTR1A (0.57) | HTR6HTR2AHTR2CHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9687692 | 0.78 | HTR1A (0.56) | HTR6HTR2AHTR2CHTR1ADRD2 | |
| SCHEMBL8415267 | 0.76 | HTR6 (0.56) | HTR6HTR2AHTR2CBRPF1HTR1A | |
| SCHEMBL10691162 | 0.75 | HTR6 (0.57) | HTR6HTR2AHTR2C | |
| SCHEMBL24878202 | 0.74 | HTR6 (1.00) | HTR6HTR2AHTR1ADRD2HTR1D | |
| SCHEMBL10505946 | 0.73 | HTR6 (0.57) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3325869 | 0.72 | HTR6 (0.65) | HTR6 | |
| SCHEMBL19650680 | 0.72 | HTR6 (0.71) | HTR6HTR2AHTR2CHTR1ADRD2 | |
| SCHEMBL14051801 | 0.72 | HTR1A (0.61) | HTR6HTR2AHTR2CHTR1AHTR1D | |
| SCHEMBL9526689 | 0.69 | APP (0.42) | HTR6BRPF1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697869-A1 | TRANSDERMAL THERAPEUTIC SYSTEMS FOR THE ADMINISTRATION OF SEROTONIN AGONISTS | LTS Lohmann Therapie-Systeme GmbH & Co. KG (DE) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026270-A1 | TRANSDERMAL THERAPEUTIC SYSTEMS FOR THE ADMINISTRATION OF SEROTONIN AGONISTS | LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG (DE) | 1994-11-24 | — | — | WO | disclosed |