Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 3/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967641 | 0.82 | SCN5A (0.42) | SCN5ASCN9ALMNAFTOGAA | |
| Hydrochloric Acid SCHEMBL10842012 | 0.80 | ALDH1A1 (0.41) | ICMTSCN5ASCN9AKMT2ALMNA | |
| SCHEMBL8967649 | 0.80 | CA12 (0.49) | MEN1KMT2AALDH1A1KDM4EKCNH2 | |
| SCHEMBL8967733 | 0.79 | KDM4E (0.43) | SCN5ASCN9AMEN1KMT2ALMNA | |
| SCHEMBL8967660 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1KDM4EKCNH2 | |
| Hydrochloric Acid SCHEMBL8968053 | 0.76 | KAT2B (0.51) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL4932077 | 0.73 | MEN1 (0.61) | MEN1KMT2AALDH1A1KDM4EDRD3 | |
| SCHEMBL8967669 | 0.71 | TSHR (0.41) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL8556050 | 0.71 | CTSB (0.43) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL8967682 | 0.70 | POLB (0.47) | ICMTMEN1LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530138-A | A PYRROLIZINE DERIVATIVE; EFFECTIVE IN THE TREATMENT OF SENILE DEMENTIA | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-06-25 | — | — | US | claimed |
| EP-0647642-A1 | 1-Azabicyclo(3.3.0)octane derivatives and their use | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1995-04-12 | — | — | EP | claimed |
| US-5530138-A | A PYRROLIZINE DERIVATIVE; EFFECTIVE IN THE TREATMENT OF SENILE DEMENTIA | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0647642-A1 | 1-Azabicyclo(3.3.0)octane derivatives and their use | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1995-04-12 | — | — | EP | disclosed |