Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL10650663 | 0.97 | HPGD (0.44) | HPGDP2RX7ALDH1A1TSHRRECQL | |
| SCHEMBL9423079 | 0.86 | HPGD (0.49) | HPGDP2RX7ALDH1A1TSHRALOX15 | |
| SCHEMBL6944180 | 0.82 | CES2 (0.57) | HPGDALDH1A1TSHRRECQLTDP1 | |
| SCHEMBL2125979 | 0.82 | ALDH1A1 (0.65) | HPGDALDH1A1TSHRRECQLTDP1 | |
| SCHEMBL21680796 | 0.82 | SLC6A2 (0.47) | HPGDP2RX7ALDH1A1NPC1RAB9A | |
| SCHEMBL11222598 | 0.81 | HPGD (0.49) | HPGDALDH1A1TSHRRECQLTDP1 | |
| SCHEMBL21482768 | 0.81 | HTR7 (0.47) | HPGDALDH1A1TSHRRECQLTDP1 | |
| SCHEMBL11195785 | 0.81 | HTT (0.54) | HPGDALDH1A1TSHRRECQLTDP1 | |
| SCHEMBL18451321 | 0.80 | HPGD (0.50) | HPGDP2RX7ALDH1A1ALOX15NPC1 | |
| SCHEMBL21780538 | 0.79 | F2R (0.56) | HPGDALDH1A1TSHRRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108778277-A | Organic compounds | 细胞内治疗公司 | 2018-11-09 | — | — | CN | disclosed |
| US-5512584-A | 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |
| US-4435419-A | Method of treating depression using azabicyclohexanes | AMERICAN CYANAMID COMPANY (US) | 1984-03-06 | — | — | US | disclosed |
| US-4352811-A | NEUROLEPTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-10-05 | — | — | US | disclosed |
| US-4282222-A | 3-Piperidino or apiperazino-1-phenyl or 1-substituted phenyl isoquinoline and antidepressant compositions thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |