Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SDCBP | O00560 | 2/20 | 0.36 |
| ▸ | SDC2 | P34741 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967161 | 0.79 | MAOA (0.41) | HPGDALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8967314 | 0.73 | SMN1; SMN2 (0.44) | HPGDCYP2C9CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL9465203 | 0.72 | MAOA (0.42) | HPGDTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19414326 | 0.69 | TEAD1 (0.36) | CYP1A2CYP2C9CYP2C19ALDH1A1RAB9A | |
| SCHEMBL19361101 | 0.69 | LMNA (0.42) | HPGDTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8258989 | 0.68 | HPGD (0.50) | HPGDTSHRCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL1800738 | 0.68 | MEN1 (0.44) | HPGDAKT1CYP1A2CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL7245398 | 0.67 | HPGD (0.49) | HPGDTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21953832 | 0.66 | CHRNA7 (0.53) | HPGDTSHRCYP3A4RAB9ALMNA | |
| SCHEMBL6566603 | 0.65 | GAA (0.56) | CYP1A2CYP2D6ALDH1A1RAB9AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553081-B1 | PESTICIDES | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| US-5326755-A | Contain cyclopropane ring | ROUSSEL UCLAF | 1994-07-05 | — | — | US | disclosed |
| EP-0553081-A1 | PESTICIDES. | ROUSSEL UCLAF (FR) | 1993-08-04 | — | — | EP | disclosed |
| WO-1991016301-A1 | PESTICIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-31 | — | — | WO | disclosed |