Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350558 | 0.82 | MAOA (0.37) | MAOAMAOBSLC6A4ALDH1A1MEN1 | |
| SCHEMBL30310011 | 0.81 | HPGD (0.49) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL16709962 | 0.80 | MTNR1A (0.37) | MAOAMAOBSLC6A4ALDH1A1MTNR1A | |
| SCHEMBL8967808 | 0.79 | HPGD (0.50) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL29321170 | 0.79 | TRPA1 (0.33) | MAOAMAOBMTNR1AMTNR1BMAPK1 | |
| SCHEMBL28375502 | 0.78 | ALDH1A1 (0.36) | MAOAMAOBALDH1A1MAPTMTNR1A | |
| SCHEMBL7362589 | 0.75 | ALDH1A1 (0.40) | MAOAMAOBSLC6A4ALDH1A1MAPT | |
| SCHEMBL8967678 | 0.74 | HAO1 (0.39) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| Bromide SCHEMBL11192117 | 0.73 | ALDH1A1 (0.39) | MAOAMAOBSLC6A4ALDH1A1MAPT | |
| SCHEMBL8967314 | 0.72 | SMN1; SMN2 (0.44) | MAOAMAOBSLC6A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553081-B1 | PESTICIDES | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| US-5326755-A | Contain cyclopropane ring | ROUSSEL UCLAF | 1994-07-05 | — | — | US | disclosed |
| EP-0553081-A1 | PESTICIDES. | ROUSSEL UCLAF (FR) | 1993-08-04 | — | — | EP | disclosed |
| WO-1991016301-A1 | PESTICIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-31 | — | — | WO | disclosed |