SCHEMBL6803138

SCHEMBL6803138

O=CCSc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.33
CTSK P43235 1/20 0.32
ALDH1A1 P00352 1/20 0.31
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6602067 0.75 KDM4E (0.35) KMT2AALDH1A1
SCHEMBL28048096 0.72 RAB9A (0.42) KMT2AMEN1GAAALDH1A1
SCHEMBL6806423 0.71 ALDH1A1 (0.42) ALDH1A1
SCHEMBL5506194 0.68 LIG1 (0.47) KMT2AMEN1ALDH1A1
SCHEMBL8967935 0.68 CTSK (0.37) KMT2AMEN1GAACTSKALDH1A1
SCHEMBL9711235 0.67 PDE7A (0.38) KMT2AMEN1GAACTSKALDH1A1
SCHEMBL6602508 0.66 POLB (0.49) KMT2AMEN1GAAALDH1A1
SCHEMBL30050744 0.65 MEN1 (0.48) KMT2AMEN1ALDH1A1DDB1CRBN
SCHEMBL4636283 0.65 MEN1 (0.48) KMT2AMEN1ALDH1A1DDB1CRBN
SCHEMBL7263840 0.65 MEN1 (0.61) KMT2AMEN1ALDH1A1DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004091724-A1 ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS WYETH (US) 2004-10-28 WO claimed