Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609119 | 0.82 | ELANE (0.41) | TLR8KDM4EALDH1A1HPGDSMN1; SMN2 | |
| Methacrylic Acid SCHEMBL8968150 | 0.80 | KDM4E (0.45) | TLR8KDM4EALDH1A1HPGDALOX15 | |
| Acridine SCHEMBL27555574 | 0.80 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL8968152 | 0.76 | TLR8 (0.48) | TLR8KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL7534418 | 0.75 | ALDH1A1 (0.42) | TLR8KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL2946336 | 0.75 | RAB9A (0.36) | TLR8KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL60866 | 0.74 | KDM4E (0.56) | TLR8KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL8786032 | 0.74 | TLR8 (0.56) | TLR8KDM4EALDH1A1HPGDALOX15 | |
| Acridine SCHEMBL18770814 | 0.74 | ALDH1A1 (0.50) | TLR8KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL6567448 | 0.72 | TLR8 (0.53) | TLR8KDM4EALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482809-A | ELECTROGRAPHY, POLYMERS WITH METAL CHELATING GROUPS AND CROSSLINKING GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-09 | — | — | US | disclosed |