Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14508529 | 0.92 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL13874684 | 0.92 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL13091568 | 0.92 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL14508528 | 0.90 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL14508531 | 0.88 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL22784190 | 0.77 | CHRNB2 (0.35) | — | |
| SCHEMBL10992013 | 0.73 | CHRNB2 (0.39) | — | |
| SCHEMBL14509708 | 0.73 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL24785049 | 0.72 | LMNA (0.30) | — | |
| SCHEMBL2266863 | 0.72 | POLB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530138-A | A PYRROLIZINE DERIVATIVE; EFFECTIVE IN THE TREATMENT OF SENILE DEMENTIA | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |