Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783648 | 0.87 | POLB (0.64) | SMN1; SMN2POLBALDH1A1LMNAMAPT | |
| SCHEMBL28573186 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBALDH1A1LMNAMAPT | |
| SCHEMBL3832407 | 0.80 | ALDH1A1 (0.77) | SMN1; SMN2POLBALDH1A1LMNAMAPT | |
| SCHEMBL3365028 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2POLBL3MBTL1GAAHDAC1 | |
| SCHEMBL1334332 | 0.76 | L3MBTL1 (0.79) | POLBALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL5048664 | 0.76 | LMNA (0.52) | SMN1; SMN2POLBALDH1A1LMNAMAPT | |
| SCHEMBL3367105 | 0.76 | GAA (0.44) | L3MBTL1GAAHDAC1MCHR1 | |
| SCHEMBL3368971 | 0.76 | GAA (0.44) | L3MBTL1GAAHDAC1MCHR1 | |
| SCHEMBL14756119 | 0.75 | SMN1; SMN2 (0.77) | SMN1; SMN2POLBALDH1A1LMNAMAPT | |
| SCHEMBL3366751 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527816-A | AGRICULTURAL USE | ROHM AND HAAS COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0529974-A1 | Fungicidal 2-aryl-2-cyano-2-(aryloxyalkyl)ethyl-1,2,4-triazoles | ROHM AND HAAS COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |