Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235204 | 0.82 | KMT2A (0.36) | ALDH1A1KDM4EGAAKMT2ACXCR1 | |
| SCHEMBL8968209 | 0.82 | KMT2A (0.36) | ALDH1A1KDM4EGAAKMT2ACXCR1 | |
| SCHEMBL18183996 | 0.81 | KMT2A (0.51) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL8968160 | 0.81 | CXCR2 (0.65) | ALDH1A1KDM4EGAAKMT2ACXCR1 | |
| SCHEMBL10376952 | 0.78 | MEN1 (0.53) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL28860755 | 0.78 | NPC1 (0.56) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL8968156 | 0.77 | GAA (0.49) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL10393667 | 0.74 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAAKMT2AMAPT | |
| SCHEMBL24755632 | 0.73 | CYP1A2 (0.61) | ALDH1A1KDM4EGAAKMT2AMAPT | |
| SCHEMBL22096847 | 0.73 | HPGD (0.45) | HPGDKMT2ACXCR1CXCR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547966-A | Aryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |