Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235204 | 1.00 | KMT2A (0.36) | KMT2ACXCR2CXCR1LPAR1F2 | |
| SCHEMBL8968189 | 0.82 | ALDH1A1 (0.43) | KMT2ACXCR2CXCR1LPAR1F2 | |
| SCHEMBL8968827 | 0.79 | CXCR2 (0.44) | KMT2ACXCR2CXCR1F2PLG | |
| SCHEMBL8968824 | 0.79 | CXCR2 (0.44) | KMT2ACXCR2CXCR1F2PLG | |
| SCHEMBL4996687 | 0.76 | KMT2A (0.44) | KMT2AF2PLGPLAUKLKB1 | |
| SCHEMBL4996691 | 0.76 | KMT2A (0.44) | KMT2AF2PLGPLAUKLKB1 | |
| SCHEMBL5005229 | 0.75 | ALDH1A1 (0.54) | KMT2ACYP1A2CYP2C19ALDH1A1USP2 | |
| SCHEMBL14257551 | 0.75 | ALDH1A1 (0.54) | KMT2ACYP1A2CYP2C19ALDH1A1USP2 | |
| SCHEMBL5005228 | 0.75 | ALDH1A1 (0.54) | KMT2ACYP1A2CYP2C19ALDH1A1USP2 | |
| SCHEMBL14257564 | 0.73 | RAB9A (0.43) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547966-A | Aryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |