Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.65 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968747 | 0.87 | CXCR1 (0.49) | CXCR2CXCR1KMT2AMEN1MAPT | |
| SCHEMBL8968218 | 0.85 | CYP11B1 (0.54) | CXCR2CXCR1KMT2AMEN1MAPT | |
| SCHEMBL8970592 | 0.84 | CXCR1 (0.47) | CXCR2CXCR1KMT2AMEN1MAPT | |
| SCHEMBL8970501 | 0.83 | CXCR1 (0.45) | CXCR2CXCR1KMT2AMEN1MAPT | |
| SCHEMBL8968156 | 0.82 | GAA (0.49) | CXCR2CXCR1ALDH1A1KDM4EGAA | |
| SCHEMBL8968824 | 0.82 | CXCR2 (0.44) | CXCR2CXCR1KMT2AMEN1MAPT | |
| SCHEMBL8968827 | 0.82 | CXCR2 (0.44) | CXCR2CXCR1KMT2AMEN1MAPT | |
| SCHEMBL8968165 | 0.81 | NPC1 (0.52) | CXCR2CXCR1KMT2AMEN1MAPT | |
| SCHEMBL8968189 | 0.81 | ALDH1A1 (0.43) | CXCR2CXCR1KMT2AMEN1MAPT | |
| SCHEMBL7489930 | 0.79 | CXCR2 (1.00) | CXCR2CXCR1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | claimed |
| US-5547966-A | Aryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-20 | — | — | US | disclosed |