Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 4/20 | 0.53 |
| ▸ | MMP13 | P45452 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968632 | 0.86 | FDFT1 (0.54) | FDFT1MMP13MMP2 | |
| SCHEMBL8968636 | 0.86 | FDFT1 (0.54) | FDFT1MMP13MMP2 | |
| SCHEMBL9432346 | 0.71 | FDFT1 (0.73) | FDFT1MMP13MMP2 | |
| SCHEMBL8931430 | 0.71 | MMP13 (0.66) | FDFT1MMP13MMP2 | |
| SCHEMBL8417749 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4E | |
| SCHEMBL8969204 | 0.71 | MMP13 (0.52) | FDFT1MMP13MMP2 | |
| SCHEMBL9432198 | 0.69 | FDFT1 (0.76) | FDFT1MMP13MMP2 | |
| SCHEMBL8969498 | 0.69 | FDFT1 (0.55) | FDFT1MMP13MMP2 | |
| SCHEMBL9433372 | 0.68 | FDFT1 (1.00) | FDFT1MMP13MMP2 | |
| SCHEMBL8969946 | 0.68 | FDFT1 (0.73) | FDFT1MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |