Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN9 | O14815 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9540578 | 0.93 | CAPN9 (0.43) | CAPN9CASP3CA12CA9CYP3A4 | |
| SCHEMBL8319980 | 0.71 | PDE7A (0.44) | CA12CA9CYP3A4MEN1KMT2A | |
| SCHEMBL15435590 | 0.70 | HTR1D (0.46) | CAPN9CASP3CYP3A4TSHRMEN1 | |
| SCHEMBL8968231 | 0.69 | CAPN9 (0.49) | CAPN9CASP3CA12CA9CYP3A4 | |
| SCHEMBL15435591 | 0.69 | LMNA (0.65) | CAPN9CASP3CYP3A4MEN1KMT2A | |
| SCHEMBL15884037 | 0.68 | ALDH1A1 (0.60) | CAPN9CASP3CA12CA9CYP3A4 | |
| SCHEMBL8968000 | 0.67 | CA12 (0.47) | CAPN9CASP3CA12CA9CYP3A4 | |
| SCHEMBL20558336 | 0.66 | MAPT (0.44) | CAPN9CASP3CA12CA9CYP3A4 | |
| SCHEMBL5259225 | 0.64 | CAPN9 (0.54) | CAPN9CASP3CA9CYP3A4MEN1 | |
| SCHEMBL31415513 | 0.63 | ALDH1A1 (0.50) | CAPN9CASP3CYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504095-A | Aminobenzosultam derivatives as lipoxygenase inhibitors | PFIZER INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0549666-B1 | NOVEL AMINOBENZOSULTAM DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER (US) | 1994-11-23 | — | — | EP | disclosed |