SCHEMBL8968345

SCHEMBL8968345

CCCCCCCNC(=O)Oc1ccc2c(=N)n3ccccc3nc2c1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.46
MGLL Q99685 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8969245 0.93 MAPT (0.46) MAPT
SCHEMBL8969392 0.85 MAPT (0.43) MAPTMGLL
SCHEMBL8969989 0.84 MAPT (0.44) MAPT
SCHEMBL8968941 0.78 MAPT (0.42) MAPT
SCHEMBL8970181 0.76 ACHE (0.46) MGLL
SCHEMBL9792268 0.73 MGLL (0.64) MGLL
SCHEMBL2329863 0.69 ALDH1A1 (0.64) MGLL
SCHEMBL2335154 0.69 ALDH1A1 (0.64) MGLL
SCHEMBL22472046 0.69 MGLL (0.73) MGLL
SCHEMBL21891896 0.69 MGLL (0.73) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486512-A LEARNING ENHANCEMENT WARNER-LAMBERT COMPANY (US) 1996-01-23 US disclosed