Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969392 | 0.88 | MAPT (0.43) | MAPT | |
| SCHEMBL8969989 | 0.83 | MAPT (0.44) | MAPT | |
| SCHEMBL8969245 | 0.78 | MAPT (0.46) | MAPT | |
| SCHEMBL8968345 | 0.78 | MAPT (0.46) | MAPT | |
| SCHEMBL8969928 | 0.70 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1GAA | |
| SCHEMBL8969448 | 0.68 | ACHE (0.37) | MAPTKDM4EALDH1A1GAA | |
| SCHEMBL8968357 | 0.66 | ACHE (0.40) | — | |
| SCHEMBL8968951 | 0.65 | KDM4E (0.50) | MAPTKDM4EALDH1A1GAA | |
| SCHEMBL8968968 | 0.65 | KDM4E (0.53) | MAPTKDM4EALDH1A1GAA | |
| SCHEMBL11644289 | 0.63 | MGLL (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |