Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968872 | 0.87 | PTPN1 (0.34) | KDM4ENPSR1MAPTPTPN1ALDH1A1 | |
| SCHEMBL8968984 | 0.83 | PDE2A (0.36) | KDM4ENPSR1MAPTPTPN1ALDH1A1 | |
| SCHEMBL8968968 | 0.75 | KDM4E (0.53) | KDM4ENPSR1MAPTHTR6ALDH1A1 | |
| SCHEMBL8969355 | 0.75 | HTR6 (0.41) | KDM4EMAPTHTR6TP53ALDH1A1 | |
| SCHEMBL8969226 | 0.72 | KDM4E (0.38) | KDM4ENPSR1MAPTPTPN1ALDH1A1 | |
| SCHEMBL8969345 | 0.72 | NR1H4 (0.39) | KDM4EMAPTHTR6TP53ALDH1A1 | |
| SCHEMBL8968970 | 0.72 | KDM4E (0.48) | KDM4ENPSR1MAPTHTR6ALDH1A1 | |
| SCHEMBL8970270 | 0.70 | HTR6 (0.41) | KDM4ENPSR1MAPTHTR6TP53 | |
| SCHEMBL8969266 | 0.69 | CYP11B1 (0.34) | KDM4ENPSR1MAPTALDH1A1GAA | |
| SCHEMBL8969761 | 0.68 | HTT (0.42) | KDM4ENPSR1MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |