Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968353 | 0.83 | ACHE (0.56) | KMT2AMEN1HDAC6POLBALDH1A1 | |
| SCHEMBL8969172 | 0.82 | ACHE (0.54) | KMT2AMEN1HDAC6POLBALDH1A1 | |
| SCHEMBL8968573 | 0.78 | POLB (0.65) | KMT2AMEN1HDAC6POLBALDH1A1 | |
| SCHEMBL5511715 | 0.77 | ALDH1A1 (0.60) | KMT2AMEN1HDAC6ALDH1A1USP2 | |
| SCHEMBL6288230 | 0.77 | MEN1 (1.00) | KMT2AMEN1HDAC6ALDH1A1USP2 | |
| SCHEMBL6216724 | 0.75 | KMT2A (0.52) | KMT2AMEN1HDAC6POLBALDH1A1 | |
| SCHEMBL5511965 | 0.75 | MEN1 (0.97) | KMT2AMEN1HDAC6POLBALDH1A1 | |
| SCHEMBL29618881 | 0.75 | MEN1 (0.97) | KMT2AMEN1HDAC6POLBALDH1A1 | |
| SCHEMBL6921153 | 0.73 | MEN1 (0.56) | KMT2AMEN1HDAC6POLBALDH1A1 | |
| SCHEMBL8969198 | 0.72 | ACHE (0.71) | KMT2AMEN1HDAC6POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |