Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968432 | 0.84 | CTSD (0.48) | PDE3BPDE3ACTSD | |
| SCHEMBL8969903 | 0.82 | PDE3B (0.45) | PDE3BPDE3AMEN1PDE2AKMT2A | |
| SCHEMBL8968564 | 0.82 | CTSD (0.30) | CTSD | |
| Hydrochloric Acid SCHEMBL9382023 | 0.81 | — | — | |
| SCHEMBL8968334 | 0.81 | HTR2A (0.31) | CTSD | |
| SCHEMBL8968377 | 0.79 | — | — | |
| SCHEMBL8968459 | 0.79 | — | — | |
| SCHEMBL8969727 | 0.78 | CTSD (0.32) | CTSD | |
| SCHEMBL8969986 | 0.77 | MAOA (0.35) | PDE3BPDE3A | |
| SCHEMBL8968314 | 0.77 | PDE3B (0.40) | PDE3BPDE3ACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |