Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 6/20 | 0.38 |
| ▸ | HTR2C | P28335 | 7/20 | 0.35 |
| ▸ | HTR2A | P28223 | 6/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969466 | 0.89 | CTSD (0.49) | ACHECTSDHTR2CHTR2AHTR2B | |
| SCHEMBL8968336 | 0.85 | — | — | |
| SCHEMBL8968791 | 0.85 | HTR2A (0.34) | PDE3BPDE3AHTR2CHTR2AHTR2B | |
| SCHEMBL8969194 | 0.84 | CTSD (0.33) | CTSD | |
| SCHEMBL8969504 | 0.83 | ACHE (0.40) | PDE3BPDE3AACHECTSDHTR2C | |
| SCHEMBL8969521 | 0.82 | CTSD (0.40) | CTSDHTR2CHTR2AHTR2B | |
| SCHEMBL9540235 | 0.81 | CTSD (0.47) | PDE3BPDE3AACHECTSD | |
| SCHEMBL8969208 | 0.78 | KLK7 (0.32) | HTR2CHTR2A | |
| SCHEMBL8969704 | 0.77 | HTR2C (0.36) | CTSDHTR2CHTR2B | |
| SCHEMBL8968559 | 0.77 | PDE3B (0.44) | PDE3BPDE3ACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |