Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968801 | 0.87 | ACHE (0.36) | MAOAACHEPDE3BPDE3A | |
| SCHEMBL8969231 | 0.80 | MAOA (0.35) | MAOAACHE | |
| SCHEMBL8968566 | 0.80 | ACHE (0.32) | ACHEKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8968414 | 0.80 | ACHE (0.36) | MAOAACHEPDE3BPDE3A | |
| SCHEMBL8969440 | 0.78 | ACHE (0.38) | ACHEPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL8968559 | 0.77 | PDE3B (0.44) | PDE3BPDE3A | |
| SCHEMBL8968432 | 0.70 | CTSD (0.48) | ACHEPDE3BPDE3A | |
| SCHEMBL8969273 | 0.70 | ACHE (0.38) | MAOAACHEALDH1A1 | |
| SCHEMBL8969665 | 0.69 | ACHE (0.48) | MAOAACHEPDE3BPDE3ANPC1 | |
| SCHEMBL8969302 | 0.68 | ACHE (0.50) | MAOAACHEPDE3BPDE3ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |