Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969678 | 0.78 | CTSD (0.39) | CYP3A4 | |
| SCHEMBL8969528 | 0.75 | PARP1 (0.35) | DRD1PARP1HTR1AACHE | |
| SCHEMBL8968445 | 0.66 | — | — | |
| SCHEMBL8969224 | 0.66 | CTSD (0.30) | — | |
| SCHEMBL8970272 | 0.66 | — | — | |
| SCHEMBL8968545 | 0.65 | ACHE (0.39) | ACHEALDH1A1CYP1A2 | |
| SCHEMBL8969582 | 0.63 | — | — | |
| SCHEMBL8969954 | 0.63 | EGFR (0.34) | — | |
| SCHEMBL8969474 | 0.63 | CTSD (0.30) | — | |
| SCHEMBL8969461 | 0.63 | DRD1 (0.33) | DRD1PARP1HTR1AACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |