Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970643 | 0.82 | IDO1 (0.45) | IDO1MAOBAPPEPHX1PYCR1 | |
| SCHEMBL683150 | 0.82 | TDP1 (0.37) | IDO1L3MBTL1RCE1ALDH1A1TAAR1 | |
| SCHEMBL683167 | 0.82 | AGXT (0.48) | IDO1MAOBNPC1RAB9ATAAR1 | |
| SCHEMBL8968738 | 0.82 | TAAR1 (0.45) | IDO1MEN1KMT2ATAAR1 | |
| SCHEMBL4686836 | 0.81 | IDO1 (0.52) | IDO1MAOBAPPPYCR1LMNA | |
| SCHEMBL8968560 | 0.81 | TAAR1 (0.41) | IDO1MAOBPYCR1MEN1NPC1 | |
| SCHEMBL682849 | 0.80 | IDO1 (0.53) | IDO1MAOBAPP | |
| SCHEMBL683166 | 0.79 | RCE1 (0.47) | IDO1MAOBMEN1MAPTKMT2A | |
| SCHEMBL4689685 | 0.76 | IDO1 (0.47) | IDO1MAOBAPPEPHX1PYCR1 | |
| SCHEMBL4060947 | 0.76 | ACACB (0.33) | IDO1MAOBPYCR1RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |