Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686836 | 0.84 | IDO1 (0.52) | IDO1APPLMNAMAOBMAOA | |
| SCHEMBL8968693 | 0.82 | IDO1 (0.47) | IDO1APPLMNAMAOBEPHX1 | |
| SCHEMBL14094034 | 0.80 | TSHR (0.44) | IDO1LMNAMAOATAAR1 | |
| SCHEMBL9510661 | 0.77 | — | — | |
| SCHEMBL4689685 | 0.74 | IDO1 (0.47) | IDO1APPLMNAMAOBEPHX1 | |
| SCHEMBL534037 | 0.73 | ADRB2 (0.50) | IDO1APPLMNAMAOBMAOA | |
| SCHEMBL28452339 | 0.72 | IDO1 (0.48) | IDO1APPMAOBMAOA | |
| SCHEMBL3043068 | 0.72 | CA2 (0.35) | TAAR1 | |
| SCHEMBL649272 | 0.71 | IDO1 (0.44) | IDO1TAAR1 | |
| SCHEMBL3128080 | 0.71 | IDO1 (0.52) | IDO1APPMAOBMAOATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |