Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Diphenylether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | BAX | Q07812 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL29175285 | 1.00 | LTA4H (0.67) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL8671677 | 0.97 | LTA4H (0.63) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL29116059 | 0.95 | LTA4H (0.60) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL28412058 | 0.94 | LTA4H (0.67) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL896890 | 0.91 | LTA4H (0.55) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL1965337 | 0.88 | LTA4H (0.75) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL360280 | 0.88 | LTA4H (0.75) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL5606885 | 0.88 | LTA4H (0.75) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL28186429 | 0.87 | HPGD (0.60) | LTA4HTSHRPARP10NR1H2BAX | |
| Acetic Acid SCHEMBL9995157 | 0.87 | PPARG (0.55) | LTA4HTSHRPARP10NR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466536-A | Glass powder for slurry, preparation method of glass powder, conductive slurry, preparation method of conductive slurry and battery | 常州聚和新材料股份有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-114392949-A | High-efficiency complete splicing glue removing process for electroplating roller | 扬州景如源电镀设备配件有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-109563363-A | For producing the preparation and technique of high conductivity copper pattern | 铜打印科技有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-106898270-A | A kind of Ultrathin flexible LED display screen | 深圳市美亚迪光电有限公司 | 2017-06-27 | — | — | CN | claimed |
| CN-103269727-B | Water-based air freshener compositions, systems, and methods of use thereof | 阿吉莱克斯香料和香水公司 | 2017-03-29 | — | — | CN | claimed |
| CN-104892904-A | Interlayer insulation material for multilayer printed circuit board and preparation process thereof | XINGNING JINGWEIJIN ELECTRONICS CO LTD | 2015-09-09 | — | — | CN | claimed |
| WO-2024242121-A1 | PATTERN FORMING METHOD AND PROCESSING LIQUID FOR METAL COMPOUND-CONTAINING FILM | 東京応化工業株式会社 | 2024-11-28 | — | — | WO | disclosed |
| CN-117466536-A | Glass powder for slurry, preparation method of glass powder, conductive slurry, preparation method of conductive slurry and battery | 常州聚和新材料股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-20230399520-A1 | A METHOD OF MAKING A THREE-DIMENSIONAL PRINTED CARBON-BONDED COMPOSITE ARTICLE | ARKEMA FRANCE (FR) | 2023-12-14 | — | — | US | disclosed |
| US-20230391936-A1 | ACTINICALLY CURABLE COMPOSITIONS FOR ABLATIVE CARBON-BONDED COMPOSITES AND ADDITIVE MANUFACTURING METHOD USING SUCH COMPOSITIONS | ARKEMA FRANCE (FR) | 2023-12-07 | — | — | US | disclosed |
| US-20230285268-A1 | AQUEOUS EMULSION BASED ANTIPERSPIRANT FORMULATION | UNION CARBIDE CORPORATION | 2023-09-14 | — | — | US | disclosed |
| EP-4232483-A1 | ACTINICALLY CURABLE COMPOSITIONS FOR ABLATIVE CARBON-BONDED COMPOSITES AND ADDITIVE MANUFACTURING METHOD USING SUCH COMPOSITIONS | ARKEMA FRANCE (FR) | 2023-08-30 | — | — | EP | disclosed |
| EP-4232282-A1 | A METHOD OF MAKING A THREE-DIMENSIONAL PRINTED CARBON-BONDED COMPOSITE ARTICLE | ARKEMA FRANCE (FR) | 2023-08-30 | — | — | EP | disclosed |
| EP-1595619-A1 | METHOD FOR INTEGRALLY FORMING RESIN MODEL | Shonan Design Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |
| CN-1603953-A | Photoresist composite and image forming method using the same | TOKYO APPLIED CHEMICAL INDUSTR (JP) | 2005-04-06 | — | — | CN | disclosed |
| US-6630742-B2 | Method for forming bumps, semiconductor device, and solder paste | FUJITSU LIMITED (JP) | 2003-10-07 | — | — | US | disclosed |
| CN-1408339-A | Skin external preparation | SHISEIDO CO LTD (JP) | 2003-04-09 | — | — | CN | disclosed |
| EP-0277244-B1 | SPHERICAL CLAY MINERAL POWDER, PROCESS FOR ITS PRODUCTION, AND COMPOSITION CONTAINING SAME | SHISEIDO CO LTD (JP) | 1994-09-21 | — | — | EP | disclosed |
| EP-0277244-A1 | SPHERICAL CLAY MINERAL POWDER, PROCESS FOR ITS PRODUCTION, AND COMPOSITION CONTAINING SAME | SHISEIDO COMPANY LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |
| EP-0270316-A2 | Topical compositions comprising 1-substituted imidazoles and NSAIDs for treatment of acne | PFIZER INC. (US) | 1988-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285268-A1 | AQUEOUS EMULSION BASED ANTIPERSPIRANT FORMULATION | ADH1A, ALOX5, PON1 | LTA4H 523/4885TSHR 1840/4885PARP10 3393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.