SCHEMBL896901

SCHEMBL896901

[NH]C(=O)c1ccccc1[C]=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.41
RAB9A P51151 1/20 0.41
ALDH1A1 P00352 6/20 0.39
ALOX15 P16050 2/20 0.39
KDM4E B2RXH2 3/20 0.37
HPGD P15428 3/20 0.37
MAPT P10636 2/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
HMGB1 P09429 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1203663 0.80 PPIA (0.43) NPC1RAB9AALDH1A1KDM4EMAPT
SCHEMBL2408127 0.79 HNF4A (0.40) NPC1RAB9AALDH1A1ALOX15KDM4E
SCHEMBL1157075 0.79 ALDH1A1 (0.40) NPC1RAB9AALDH1A1ALOX15KDM4E
SCHEMBL8385 0.79 ALDH1A1 (0.59) NPC1RAB9AALDH1A1ALOX15KDM4E
SCHEMBL302106 0.77 NPC1 (0.33) NPC1RAB9AALDH1A1ALOX15
SCHEMBL11594420 0.77 NPC1 (0.60) NPC1RAB9AALDH1A1ALOX15KDM4E
SCHEMBL11411301 0.77 ALDH1A1 (0.39) NPC1RAB9AALDH1A1ALOX15KDM4E
SCHEMBL101186 0.77 ALDH1A1 (0.50) NPC1RAB9AALDH1A1ALOX15KDM4E
SCHEMBL11418729 0.77 ALDH1A1 (0.39) NPC1RAB9AALDH1A1ALOX15KDM4E
SCHEMBL151086 0.77 FFAR1 (0.49) NPC1RAB9AALDH1A1ALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290474-A Method for preparing glufosinate-ammonium by using glycine as raw material 山东泰和科技股份有限公司 2024-07-05 CN claimed
CN-108192014-A Super absorbent resin containing acid deodoriging properties 宜兴丹森科技有限公司 2018-06-22 CN claimed
CN-1298737-C Synthesis method of dipeptide containing L-glutamine NANJING UNIVERSITY OF TECHNOLOGY (CN) 2007-02-07 CN claimed
EP-0620216-B1 Benzamide derivatives and their use as vasopressin antagonists FUJISAWA PHARMACEUTICAL CO (JP) 2003-01-08 EP claimed
WO-2001056385-A1 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA ARTHUR M (US) 2001-08-09 WO claimed
EP-0813510-A4 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA ARTHUR M (US) 2000-07-26 EP claimed
US-5763413-A Lewis-associated compound, process for producing the same, and anti-inflammatory MECT CORPORATION (JP) 1998-06-09 US claimed
EP-0813510-A1 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA, Arthur M. (US) 1997-12-29 EP claimed
EP-0697407-B1 Pyrimidinedione derivatives and antiarrhythmic compositions containing same MITSUI TOATSU CHEMICALS (JP) 1997-06-25 EP claimed
WO-1996027572-A1 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA ARTHUR M (US) 1996-09-12 WO claimed
EP-0094095-B1 BICYCLIC CARBOXYLIC ACIDS AND THEIR ALKYL AND ARALKYL ESTERS F. HOFFMANN-LA ROCHE AG (CH) 1990-09-19 EP claimed
US-4808713-A Anthypertensive pyridazo [1,2-a][1,2]diazepines HOFFMAN-LA ROCHE INC. (US) 1989-02-28 US claimed
US-4772701-A Pyridazo[1,2]pyridazines and pyrazolo[1,2]pyridazines as antihypertensives HOFFMANN-LA ROCHE INC. (US) 1988-09-20 US claimed
US-4658024-A Pyrazolo [1,2-a][1,2]-diazepines useful as antihypertensives HOFFMANN-LA ROCHE INC. (US) 1987-04-14 US claimed
US-4512924-A HYPOTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1985-04-23 US claimed
EP-0094095-A2 Bicyclic carboxylic acids and their alkyl and aralkyl esters F. HOFFMANN-LA ROCHE AG (CH) 1983-11-16 EP claimed
US-4377518-A Azo dyestuffs derived from polycyclo-hetercyclic coupler components BAYER AKTIENGESELLSCHAFT (DE) 1983-03-22 US claimed
US-4308380-A 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-12-29 US claimed
US-4014874-A Process for the manufacture of 3-substituted thiomethyl-7-amino-2-cephem-4-carboxylic acid compound CIBA-GEIGY CORPORATION (US) 1977-03-29 US claimed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US claimed