Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808280 | 0.84 | NPC1 (0.40) | NPC1RAB9AALDH1A1ALOX15 | |
| SCHEMBL4634722 | 0.80 | NPC1 (0.32) | NPC1RAB9AALDH1A1ALOX15 | |
| SCHEMBL1157075 | 0.79 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1ALOX15 | |
| SCHEMBL896901 | 0.77 | NPC1 (0.41) | NPC1RAB9AALDH1A1ALOX15 | |
| SCHEMBL4632881 | 0.77 | NPC1 (0.31) | NPC1RAB9AALDH1A1ALOX15 | |
| SCHEMBL5565721 | 0.75 | NR4A1 (0.31) | NPC1RAB9ANR4A1NR4A2NR4A3 | |
| SCHEMBL8385 | 0.74 | ALDH1A1 (0.59) | NPC1RAB9AALDH1A1ALOX15NR4A1 | |
| SCHEMBL101186 | 0.73 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1ALOX15 | |
| SCHEMBL11418729 | 0.73 | ALDH1A1 (0.39) | NPC1RAB9AALDH1A1ALOX15 | |
| SCHEMBL11411301 | 0.73 | ALDH1A1 (0.39) | NPC1RAB9AALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279236-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORP (JP) | 2021-01-06 | — | — | EP | claimed |
| US-10647723-B2 | Thiochromene type compound and use thereof | Sogang University Research Foundation (KR) | 2020-05-12 | — | — | US | claimed |
| JP-2012500804-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2328619-A2 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | Baxter International Inc. (US) | 2011-06-08 | — | — | EP | claimed |
| WO-2010022320-A2 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | BAXTER INTERNATIONAL INC. (US) | 2010-02-25 | — | — | WO | claimed |
| EP-2101585-A1 | DIALKYLAMINO ALKYL ESTERS OF PIVAGABINE AS MEDICAMENTS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | Cenerx Biopharma, Inc. (US) | 2009-09-23 | — | — | EP | claimed |
| WO-2008066874-A1 | DIALKYLAMINO ALKYL ESTERS OF PIVAGABINE AS MEDICAMENTS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | CENERX BIOPHARMA, INC. (US) | 2008-06-05 | — | — | WO | claimed |
| EP-1812453-A1 | METHOD OF PREPARING OR SYNTHESIZING POLYAZAMACROCYCLE DERIVATIVES | Therapharm GmbH (CH) | 2007-08-01 | — | — | EP | claimed |
| WO-2006045546-A1 | METHOD OF PREPARING OR SYNTHESIZING POLYAZAMACROCYCLE DERIVATIVES | THERAPHARM GMBH (CH) | 2006-05-04 | — | — | WO | claimed |
| WO-2004007407-A2 | FLUOROUS TAGGING AND SCAVENGING REACTANTS AND METHODS OF SYNTHESIS AND USE THEREOF | FLUOROUS TECHNOLOGIES INCORPORATED (US) | 2004-01-22 | — | — | WO | claimed |
| US-5514794-A | DERIVATIZED DRUGS WITH MALONATE LINKER, THE DRUG BEING LINKED THROUGH METHYLENE TO THE 2-POSITION CARBON OF MALONATE; THESE ARE INTERMEDIATES FOR THE CONJUGATES | ELI LILLY AND COMPANY (US) | 1996-05-07 | — | — | US | claimed |
| EP-3604385-B1 | HETEROBIFUNCTIONAL MONODISPERSED POLYETHYLENE GLYCOL AND CONJUGATE USING THE SAME | NOF CORP (JP) | 2024-05-01 | — | — | EP | disclosed |
| CN-114450324-B | Heterobifunctional monodisperse polyethylene glycols with peptide linkers | 日油株式会社 | 2024-02-27 | — | — | CN | disclosed |
| US-11905367-B2 | Branched monodispersed polyethylene glycol, intermediate and methods for producing same | NOF CORPORATION (JP) | 2024-02-20 | — | — | US | disclosed |
| WO-2023204256-A1 | ACETAL-TYPE RELEASABLE POLYOXYETHYLENE DERIVATIVE, PRODUCTION METHOD THEREOF AND ACETAL-TYPE RELEASABLE POLYOXYETHYLENE CONJUGATE | 日油株式会社 | 2023-10-26 | — | — | WO | disclosed |
| EP-0368668-A2 | Antibody-drug conjugates | ELI LILLY AND COMPANY (US) | 1990-05-16 | — | — | EP | disclosed |
| EP-0283938-A1 | Silver halide color photographic material | Fuji Photo Film Co., Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |
| EP-0254120-A2 | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1988-01-27 | — | — | EP | disclosed |
| EP-0242847-A2 | Tracers for use in flecainide fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1987-10-28 | — | — | EP | disclosed |
| US-4668616-A | Process for hardening gelatin | FUJI PHOTO FILM CO., LTD. (JP) | 1987-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647723-B2 | Thiochromene type compound and use thereof | TMT1A, TST, TTI1 | NPC1 3533/4885RAB9A 2730/4885ALDH1A1 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.