Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968531 | 0.80 | ACHE (0.33) | ACHE | |
| SCHEMBL8968441 | 0.80 | MAOA (0.34) | ACHEMAOA | |
| SCHEMBL8968414 | 0.80 | ACHE (0.36) | ACHEMAOA | |
| SCHEMBL8968545 | 0.79 | ACHE (0.39) | ACHEKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8968566 | 0.79 | ACHE (0.32) | ACHEKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8969054 | 0.74 | — | — | |
| SCHEMBL8970442 | 0.70 | KDM4E (0.30) | ACHEKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8969306 | 0.69 | — | — | |
| SCHEMBL8969686 | 0.69 | PDE3B (0.45) | — | |
| SCHEMBL8968716 | 0.69 | CTSD (0.46) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |