Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968545 | 0.82 | ACHE (0.39) | ACHE | |
| SCHEMBL8969032 | 0.80 | ACHE (0.31) | MAOAACHE | |
| SCHEMBL8968687 | 0.80 | MAOA (0.34) | MAOAACHE | |
| SCHEMBL8969231 | 0.80 | MAOA (0.35) | MAOAACHE | |
| SCHEMBL8968403 | 0.79 | — | — | |
| SCHEMBL8968414 | 0.79 | ACHE (0.36) | MAOAACHE | |
| SCHEMBL8969417 | 0.71 | MAOA (0.36) | MAOAACHE | |
| SCHEMBL8968558 | 0.70 | ACHE (0.48) | MAOAACHE | |
| SCHEMBL8968351 | 0.70 | CTSD (0.46) | ACHE | |
| SCHEMBL8969163 | 0.69 | ACHE (0.50) | MAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |