SCHEMBL8969194

SCHEMBL8969194

Clc1cc2c(cc1Cl)N=C1C3CC4CC(C3)CC(C4)N1C2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSD P07339 2/20 0.33
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8969466 0.84 CTSD (0.49) CTSD
SCHEMBL8968314 0.84 PDE3B (0.40) CTSD
SCHEMBL8970140 0.81 CTSD (0.32) CTSD
SCHEMBL8969231 0.79 MAOA (0.35) CTSDHSD11B1
SCHEMBL8968564 0.79 CTSD (0.30) CTSD
SCHEMBL8969208 0.79 KLK7 (0.32)
SCHEMBL8969577 0.78 CTSD (0.34) CTSD
SCHEMBL8969704 0.78 HTR2C (0.36) CTSD
SCHEMBL8968791 0.78 HTR2A (0.34)
Hydrochloric Acid SCHEMBL9382023 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486512-A LEARNING ENHANCEMENT WARNER-LAMBERT COMPANY (US) 1996-01-23 US disclosed
EP-0597956-A1 QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS WARNER-LAMBERT COMPANY (US) 1994-05-25 EP disclosed
WO-1993003034-A1 QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS WARNER-LAMBERT COMPANY (US) 1993-02-18 WO disclosed