Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969761 | 0.85 | HTT (0.42) | GAALMNAHTTPOLBMEN1 | |
| SCHEMBL8969401 | 0.85 | PDE2A (0.34) | GAALMNAHTTPOLBMEN1 | |
| SCHEMBL8968968 | 0.76 | KDM4E (0.53) | GAALMNAPOLBMEN1KMT2A | |
| SCHEMBL8969226 | 0.73 | KDM4E (0.38) | GAAPOLBMEN1KMT2AKDM4E | |
| SCHEMBL8970270 | 0.73 | HTR6 (0.41) | GAAPOLBMEN1KMT2AKDM4E | |
| SCHEMBL8969266 | 0.70 | CYP11B1 (0.34) | GAAPOLBMEN1KMT2AKDM4E | |
| SCHEMBL8969345 | 0.70 | NR1H4 (0.39) | GAAPOLBKDM4EALDH1A1NPC1 | |
| SCHEMBL8969355 | 0.70 | HTR6 (0.41) | GAALMNAPOLBMEN1KMT2A | |
| SCHEMBL8969480 | 0.70 | HTR6 (0.39) | GAAPOLBMEN1KMT2AKDM4E | |
| SCHEMBL8968872 | 0.67 | PTPN1 (0.34) | GAAPOLBMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |