Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805463 | 0.87 | CYP1A2 (0.54) | MEN1KMT2AHPGDHTTHDAC3 | |
| SCHEMBL30982230 | 0.80 | CYP2D6 (0.46) | MEN1KMT2ATAAR1HPGDHTT | |
| SCHEMBL8969478 | 0.79 | TAAR1 (0.51) | MEN1KMT2ATAAR1HPGDALDH1A1 | |
| SCHEMBL9379406 | 0.79 | MEN1 (0.46) | MEN1KMT2ATAAR1HPGDGAA | |
| SCHEMBL7320109 | 0.78 | HDAC3 (0.46) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL11530821 | 0.78 | LMNA (0.47) | MEN1KMT2AHPGDHTTHDAC3 | |
| SCHEMBL24496758 | 0.78 | HDAC3 (0.52) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29587707 | 0.78 | HDAC3 (0.52) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24496757 | 0.78 | HDAC3 (0.52) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11471664 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2ATAAR1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585392-A | TREATING OR PREVENTING STROKES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5506246-A | Method for treating depression using substituted aminomethyltetralins and their heterocyclic analogues | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-09 | — | — | US | disclosed |
| US-5300523-A | Binding serotonin receptors, treating nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5137901-A | For binding 5-HT 1 receptors; treating central nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |