SCHEMBL8969260

SCHEMBL8969260

CCC(C)CC(=O)OC1CSCC1O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
STING1 Q86WV6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970719 0.85 MMP1 (0.33) STING1
SCHEMBL8970236 0.82 ELANE (0.31) ELANE
SCHEMBL8970162 0.80 CHRM2 (0.39) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8969828 0.77 ALDH1A1 (0.39)
SCHEMBL8970369 0.74 NAAA (0.42)
SCHEMBL8970473 0.72 NAAA (0.51)
SCHEMBL28445297 0.71 MEN1 (0.40) ELANECHRM2CHRM4CHRM1CHRM3
SCHEMBL8970352 0.70 KMT2A (0.50) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8970071 0.69 CHRM2 (0.34) ELANECHRM2CHRM4CHRM1CHRM3
SCHEMBL8970456 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed