Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969903 | 0.86 | PDE3B (0.45) | CTSDOPRM1OPRL1PDE3BPDE3A | |
| SCHEMBL8968760 | 0.86 | PDE3B (0.34) | OPRM1OPRL1PDE3BPDE3AHTR2A | |
| SCHEMBL8969508 | 0.84 | PDE3B (0.33) | CTSDPDE3BPDE3ALMNACYP1A2 | |
| SCHEMBL8970030 | 0.82 | CTSD (0.50) | CTSDOPRM1OPRL1PDE3BPDE3A | |
| SCHEMBL8969685 | 0.81 | — | — | |
| SCHEMBL8969218 | 0.80 | OPRM1 (0.31) | OPRM1OPRL1 | |
| SCHEMBL8969608 | 0.79 | OPRM1 (0.33) | OPRM1OPRL1 | |
| SCHEMBL8969072 | 0.79 | OPRM1 (0.36) | CTSDOPRM1OPRL1PDE3BPDE3A | |
| SCHEMBL8968379 | 0.79 | HTR2A (0.38) | OPRM1OPRL1HTR2AHTR2CHTR2B | |
| SCHEMBL8969496 | 0.78 | HTR2C (0.36) | CTSDOPRM1OPRL1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |