Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968497 | 0.87 | ACHE (0.47) | ACHE | |
| SCHEMBL8969789 | 0.83 | ACHE (0.46) | ACHEDRD2DRD4DRD3 | |
| SCHEMBL8969632 | 0.81 | ACHE (0.40) | ACHEDRD2DRD4DRD3 | |
| SCHEMBL8968412 | 0.77 | ACHE (0.46) | ACHE | |
| SCHEMBL8969711 | 0.76 | ACHE (0.43) | ACHEDRD2DRD4DRD3 | |
| SCHEMBL8968631 | 0.70 | ACHE (0.38) | ACHE | |
| SCHEMBL8969199 | 0.68 | SPR (0.37) | ACHE | |
| SCHEMBL8968484 | 0.68 | ACHE (0.54) | ACHEDRD4 | |
| SCHEMBL8969316 | 0.66 | ACHE (0.32) | ACHE | |
| SCHEMBL8968233 | 0.66 | ACHE (0.57) | ACHEDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |