Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968517 | 0.83 | CTSD (0.43) | CTSDPDE4BPDE4DMAPTCYP3A4 | |
| SCHEMBL8969419 | 0.82 | — | — | |
| SCHEMBL8970140 | 0.79 | CTSD (0.32) | CTSD | |
| SCHEMBL8969528 | 0.78 | PARP1 (0.35) | CTSDHTR2C | |
| SCHEMBL8969818 | 0.78 | PDE10A (0.33) | ABCB1 | |
| SCHEMBL8968239 | 0.77 | — | — | |
| SCHEMBL8969263 | 0.77 | CTSD (0.33) | CTSDHTR2C | |
| SCHEMBL8969764 | 0.77 | PDE3B (0.34) | HTR2C | |
| SCHEMBL8968749 | 0.75 | CTSD (0.38) | CTSDABCB1PDE4DCYP3A4SIGMAR1 | |
| SCHEMBL8969504 | 0.74 | ACHE (0.40) | CTSDHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |