Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 8/20 | 0.44 |
| ▸ | PNMT | P11086 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969736 | 0.89 | CTSD (0.34) | CTSDPNMTTDP2 | |
| SCHEMBL8969486 | 0.81 | MAPK1 (0.34) | — | |
| SCHEMBL8968478 | 0.78 | ACHE (0.43) | CTSDPNMT | |
| SCHEMBL11774305 | 0.75 | CA1 (0.34) | CTSD | |
| SCHEMBL8970367 | 0.74 | HTR7 (0.31) | — | |
| SCHEMBL10767417 | 0.73 | HPGD (0.41) | CTSD | |
| SCHEMBL8969612 | 0.69 | PDE3B (0.34) | — | |
| SCHEMBL8969494 | 0.69 | KDM4E (0.30) | PNMT | |
| SCHEMBL8969070 | 0.69 | KDM4E (0.33) | — | |
| SCHEMBL8969143 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |