Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 7/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 4/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969644 | 0.89 | CTSD (0.44) | CTSDPNMTTDP2 | |
| SCHEMBL8969494 | 0.78 | KDM4E (0.30) | PNMTALDH1A1 | |
| SCHEMBL8969612 | 0.78 | PDE3B (0.34) | ALDH1A1 | |
| SCHEMBL8968669 | 0.74 | NPSR1 (0.31) | — | |
| SCHEMBL11774305 | 0.72 | CA1 (0.34) | CTSD | |
| SCHEMBL8969486 | 0.72 | MAPK1 (0.34) | ALDH1A1 | |
| SCHEMBL8968478 | 0.69 | ACHE (0.43) | CTSDPNMTALDH1A1 | |
| SCHEMBL8969002 | 0.67 | ACHE (0.39) | ALDH1A1HRH3 | |
| SCHEMBL8969143 | 0.67 | — | — | |
| SCHEMBL892966 | 0.66 | TDP2 (0.36) | NOTUMALDH1A1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |