Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969038 | 0.72 | ALDH1A1 (0.35) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL544039 | 0.67 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8969371 | 0.58 | ACHE (0.43) | ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8969583 | 0.58 | KDM4E (0.30) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8968208 | 0.56 | PDE3B (0.31) | PDE3BPDE3A | |
| SCHEMBL194376 | 0.55 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12165348 | 0.53 | CYP1A2 (0.33) | ALDH1A1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19314858 | 0.53 | ALDH1A1 (0.36) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8207728 | 0.51 | CYP1A2 (0.39) | ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL31294885 | 0.51 | RECQL (0.43) | ALDH1A1HPGDLMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |